Fig. 1: Structural alignment illustrates the transducer specificity of MOR.
From: Gz and β-arrestin 1 signaling in the μ-opioid receptor
a Signaling diversity of MOR mediated by various transducers. b Structural superimposition of MOR bound to βarr1, Gz and Gi (PDB: 6DDF). Arrows indicate the movement of TM1 and helix 8. H8, helix 8.
