Fig. 3

Association of double or single isoform MBL deficiency with ischemic outcome at 48 h. a The “healthy score” was obtained by rating mice from 4 (good outcome) to 1 (poor outcome) based on quartiles of neuroscore, ischemic volume and neuronal count (summed over the cortex and striatum quantifications). The final score was the sum of the weighted scores of the three parameters, e.g., the neuroscore accounted for 50% and the ischemic volume and neuronal count each accounted for 25% of the final score. b Association (odds ratio; 95% confidence interval) between the genotype and “healthy score”. The odds ratio was calculated by a Chi-square test using the Woolf logit interval for computing the 95% confidence interval (CI 95%), stratifying mice in terms of good outcome (defined as a score = 4) vs. bad outcome (score < 4). Only MBL^−/− mice were significantly associated with a good outcome