Table 1 Patients and transplant characteristics

From: Loss of Lkb1 impairs Treg function and stability to aggravate graft-versus-host disease after bone marrow transplantation

Characteristics

Patients

46

Gender

 Male/Female

27/19

Median age (range, year)

35 (7–63)

Diagnosis

 AML

14

 ALL

12

 MDS

10

 AA

7

 Other

3

Donor type

 MSD

20

 MUD

3

 MMSD

23

GVHD prophylaxis

 CsA based

19

 FK506 based

27

Conditioning regimen

 BCFA

27

 FC + ATG

5

 TCFA

14

Acute GVHD grade

 0

26

 I

5

 II

3

 III

6

 IV

6

GVHD target organ

 Skin

13

 Liver

8

 Intestine

15

 Oral cavity

1

  1. MSD matched sibling donor, MUD matched unrelated donor, MMSD mismatched sibling donor, CsA cyclosporin, FK506 tacrolimus, BCFA busulfan, cyclophosphamide, fludarabine, Ara-c, FC + ATG fludarabine, cyclophosphamide, antithymocyte globulin, and TCFA total body irradiation, cyclophosphamide, fludarabine, Ara-c
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