Fig. 2
From: Enforced PGC-1α expression promotes CD8 T cell fitness, memory formation and antitumor immunity
Enforced PGC-1α expression does not favor resident memory T cell generation. a Schematic representation of Listeria-Ova infection. A total of 20,000 CD45.1 OT-1 cells transduced with PGC-1α or SCR were transferred into CD45.2 naive recipients followed by 2000 CFU of Listeria-Ova. b Percentage of the CD103+ CD69+ population in the spleen and liver on day 15 post infection (pooled data from two experiments). c Representative histograms illustrating CD103 and CD69 expression in the endogenous T cell population and the transferred transduced OT-1 T cells from spleen and liver. b, c Gated on CD8+ CD45.1+ GFP+. Data are representative of two independent experiments and are presented as the mean ± SD (7–9 mice per group). *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001
