Fig. 6

Cytokines and chemokines in BALF samples collected from rhesus macaques immunized with two doses of CoVLP, CoVLP + CpG, or CoVLP + AS03 on day 6 post challenge with SARS-CoV-2. Dotted lines indicate the limit of detection for each cytokine/chemokine. Individual data, medians (lines), and 75th/25th interquartiles (boxes) are represented. Statistical comparisons were performed using the nonparametric Kruskal–Wallis test followed by the Dunn post hoc multiple comparisons test (*p < 0.05)