Fig. 2: Analysis of PD-1 and CTLA-4 ligand-expressing cells in lung tumor patients. | Cellular & Molecular Immunology

Fig. 2: Analysis of PD-1 and CTLA-4 ligand-expressing cells in lung tumor patients.

From: Macrophages regulate PD-1 and CTLA-4 expression on ILC2s and their responsiveness in the tumor microenvironment

Fig. 2

A Concentrations of soluble CD86, PD-L1 and PD-L2 ligands in HD PB, PB and mPE of patients with lung tumors. tSNE plots (B) and average proportion (C) within each sample type of each cell subset color-coded by subset. D CD80, CD86, PD-L1 and PD-L2 membrane expression on macrophages from mPE was analyzed by flow cytometry. FACS histograms are shown for one representative donor. FMO is shown as a negative control. Each dot in (A) represents one donor. One-way ANOVA was performed in (A); *p < 0.05, **p < 0.01, ****p < 0.0001

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