Table 1 Characteristics of ADENS and TMSP-ADENS

From: Amphiphilic dendrimer engineered nanocarrier systems for co-delivery of siRNA and paclitaxel to matrix metalloproteinase-rich tumors for synergistic therapy

 

Diameter (nm)

PDI

Zeta (mV)

E.E of PTX (%)

Blank ADENS

131.4 ± 3.67

0.147 ± 0.04

17.80 ± 7.23

/

ADENS/siRNA

140.6 ± 4.46

0.149 ± 0.03

14.85 ± 5.14

/

ADENS/siRNA/PTX

138.6 ± 9.55

0.147 ± 0.02

10.81 ± 2.08

90.97 ± 3.33

TMSP-ADENS/siRNA/PTX

140.5 ± 1.67

0.149 ± 0.01

10.53 ± 4.91

91.03 ± 4.21

  1. aData are expressed as the mean ± SD value for at least three different preparations
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