Fig. 5

Gd3+/ Yb3+/ Er3+ co-doped upconversion nanoparticles for multimodality imaging: a Whole-body two-dimensional projection, upconversion luminescence (UCL) and bright-field images of the liver. b Quantization analysis of UCL signals of the liver section. Black arrows point to the background (counts ~0), and red arrows point to the signal (counts > 4095). Adapted with permission from Zhou et al.73 (copyright 2011 Elsevier)