Fig. 1: Fabrication, photothermal effect, and magnetic property of CCM/IDINPs. | NPG Asia Materials

Fig. 1: Fabrication, photothermal effect, and magnetic property of CCM/IDINPs.

From: Bioinspired tumor-homing nanosystem for precise cancer therapy via reprogramming of tumor-associated macrophages

Fig. 1: Fabrication, photothermal effect, and magnetic property of CCM/IDINPs.

a Scheme illustrating the preparation process for CCM/IDINPs. TEM images of (b) SPIO, SPIO@DOX, IDINPs, CCM, CCM/IDINPs and individual nanoparticle of the CCM/IDINP system; scale bar = 20 nm and 100 nm. c DF-TEM images of CCM/IDINPs, scale bar = 25 nm. Temperature curves of CCM/IDINPs (d) and ICG (e) after NIR laser irradiation with the laser density set at 0.5, 0.75 and 1.0 W/cm2 for 1200 s. f Representative images of CCM/IDINPs and ICG with continuous irradiation with an NIR laser at different time points (1.0 W/cm2). g Temperature changes of CCM/IDINPs and ICG solution with NIR laser (1.0 W/cm2) switch-on and switch-off irradiation for 10 cycles. h T2-weighted MR images of CCM/IDINPs, IDINPs, and SPIO with different Fe concentrations ranging from 25 to 400 μM. i Fitted curves of the T2-weighted relaxation rate of CCM/IDINPs, IDINPs, and SPIO versus Fe concentration

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