Fig. 3: Cellular patterns and their in vivo biocompatibility.
From: A hierarchically ordered compacted coil scaffold for tissue regeneration
a–c SEM images (1), epifluorescence microscopy images (2), 2D (3) and 3D (4) confocal microscopy images of the patterned PCL fabric with EGFP-hMSC-TERT cells after 7 days (a, pattern 1.1; b, pattern 2.1; c, pattern 3.1). (Blue: nucleus, green: f-actin). d LDH activity measured from culture media collected 24 h after seeding EGFP-hMSC-TERT cells onto patterned PCL scaffolds (n = 6). e Cell proliferation on the patterned PCL fabric (n = 6). f, g Relative IL-6 (f) and TNF-α (g) levels in serum from healthy mice before PCL implantation and on days 3 and 7 after implantation. n = 3; *p ≤ 0.05; **p ≤ 0.005; ***p ≤ 0.001.
