Table 1 Studies on using perfluorocarbons to improve PDT efficacy.
From: Strategies to improve photodynamic therapy efficacy by relieving the tumor hypoxia environment
Perfluorocarbon | Chemical formula | Status | Delivery system | Combined photosensitizer/drug | Reference |
|---|---|---|---|---|---|
Perfluorohexane | C6F14 | Preclinical | Nanodroplet | IR780 | |
| Â | Â | Preclinical | Nanoemulsions | fluorous porphyrin | |
| Â | Â | Preclinical | Nanodroplet | Ce6 | |
Perfluorotributylamine | C12F27N | Preclinical | Nanoparticles | IR780 | |
Perfluorooctyl bromide | C8BrF17 | Preclinical | Nanocapsules | IR780 | |
| Â | Â | Preclinical | Nanoliposome | ICG | |
| Â | Â | Preclinical | Nanodroplet | Ce6 | |
Perfluoropropane | C3F8 | Clinical | Gas | Verteporfin | |
Perfluoropentane | C5F12 | Preclinical | Nanocubes | HPB |
