Fig. 4: Effect of NP shape on the nano-bio interface interactions between NPs and the cell membrane. | NPG Asia Materials

Fig. 4: Effect of NP shape on the nano-bio interface interactions between NPs and the cell membrane.

From: Simulation of nanoparticles interacting with a cell membrane: probing the structural basis and potential biomedical application

Fig. 4: Effect of NP shape on the nano-bio interface interactions between NPs and the cell membrane.

a NPs of various shapes (rod, disc, and sphere) and the composition and structure of the model apical membrane. b Interactions of NPs of various shapes with the apical lipid layer. Reproduced with permission30. Copyright 2020, Royal Society of Chemistry. c Computational models of oblate, prolate, cubic, disc-like, and rod-like NPs and the cell membrane. d Wrapping time as a function of bending constant for oblate, prolate, and spherical NPs. Reproduced with permission31. Copyright 2019, American Chemical Society. Endocytosis kinetics of NPs of various shapes for the invagination stage (e) and wrapping stage (f). Reproduced with permission33. Copyright 2012, Elsevier.

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