Fig. 4: HA-Based MNs.
From: Microneedles for controlled and sustained intraocular drug delivery
a Schematic of DL-MNs using MeHA and HA (left) Confocal image DL-MNs loading immunoglobulin G colored with Alexa Fluor 680 (red) and 488 (green) Scale bar: 100 μm (right). Reproduced with permission from ref. 18. b Drug release distribution images of DL-MNs in agarose hydrogel. Reproduced with permission from ref. 18. c Time-dependent dissolution of MNs with different PLA contents (Scale bar: 200 μm). Reproduced with permission from ref. 51. d H&E images of the cornea before and after insertion of 30% PLA MNs (Scale bar: 200 μm). Reproduced with permission from ref. 51.
