Abstract
In our effort to find antioxidants from the higher fungi, we isolated three new compounds (1–3) with a known compound, spirobenzofuran (4), from the culture broth of Hericium coralloides. Bioassay-guided fractionation led to the isolation of these compounds, and we determined the chemical structures through spectroscopic methods. These compounds exhibited antioxidant activity in the range of IC50 values of 29-66 μM in the 2,2’-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical-scavenging assay.
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Acknowledgements
This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT and future Planning (NRF-2016R1A2B2014430). We thank Ms. Ji-Young Oh, Center for University Research Facility (CURF) at Chonbuk National University, for NMR measurement. This research was supported by “Research Base Construction Fund Support Program” funded by Chonbuk National University in 2017.
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Kim, JY., Woo, EE., Lee, IK. et al. New antioxidants from the culture broth of Hericium coralloides. J Antibiot 71, 822–825 (2018). https://doi.org/10.1038/s41429-018-0067-6
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DOI: https://doi.org/10.1038/s41429-018-0067-6
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