Fig. 4
From: Aminomethyl spectinomycins: a novel antibacterial chemotype for biothreat pathogens
Survival of BALB/c mice infected i.n. with 2 × 104 CFU B. mallei FMH. Treatment with 1950 (50 mg kg−1, BID) was initiated at 1, 6, 24, or 48 h post-infection and was administered s.c. for 14 days. Control mice were treated with saline (untreated) or spectinomycin (50 mg kg−1, BID) starting at 1 h post-infection. 1950 (1 h) group: n = 8; all other groups: n = 10. #Significantly different from untreated control group (P < 0.05)
