Table 1 The effect of sub-MIC of celastrol, thymol or combination of them on the MIC of meropenem against K.pneumoniae isolates

From: In vitro activity of celastrol in combination with thymol against carbapenem-resistant Klebsiella pneumoniae isolates

Isolate’s No.

MEM

MEM + Celastrol

MEM + Thymol

MEM + Celastrol + Thymol*

11k

256

256

128(2)

32(8)

13k

256

256

128(2)

8(32)

14k

32

32

16(2)

<1(>32)

17k

512

512

256(2)

128(4)

35k

64

64

32(2)

<1(>64)

60k

128

128

128(0)

32(4)

68k

256

256

256(0)

64(4)

85k

128

128

128(0)

32(4)

  1. MEM meropenem, (fold change in MEM-MIC was listed between brackets)