Fig. 4 | The Journal of Antibiotics

Fig. 4

From: Prophylactic administration of ivermectin attenuates SARS-CoV-2 induced disease in a Syrian Hamster Model

Fig. 4

Prophylactic administration of ivermectin reduces the severity of pathological changes associated with SARS-CoV-2 infection. a Plasma titers of neutralizing antibodies on day 0 and 10 in vehicle-treated or IVM-treated hamsters (n = 5 per group) infected with SARS-CoV-2. Neutralizing antibody titers are expressed as a reciprocal of the highest dilution of the test plasma that completely inhibited the cytopathic effect. b Zinc concentrations in lungs from vehicle-treated or IVM-treated hamsters (n = 5 per group) after SARS-CoV-2 infection. Data are presented as the means ± SEM of duplicates. *P < 0.05 by Student’s t-test

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