Table 4 Comparison of biochemical parameters according to Crohn’s disease activity in patients in remission and active disease.

From: Evaluation of serum and dietary profiles of vitamin B12 and folate and their association with systemic complications in patients with Crohn’s disease

Variables

Remission

Activity

p-value

Vitamin B12 (pmol/L) (mean ± SD)

306.37 ± 155.63

300.09 ± 188.44

0.719

Clinical deficiency (%)

4.17

25.93

0.033

Metabolic deficiency/metabolic risk (%)

79.17

55.56

0.074

Metabolic safety (%)

16.67

18.52

0.863

Folate (ng/mL) (mean ± SD)

12.7 ± 4.09

9.82 ± 3.8

0.012

Clinical deficiency/risk of insufficiency (%)

0

11.11

0.092

Metabolic safety/elevated (%)

100

88.89

0.092

Non-HDL cholesterol (mean ± SD)

132.23 ± 37.03

92.92 ± 24.71

0.003

Very high/high (%)

15.38

0

0.127

Desirable (%)

38.46

0

0.010

Optimal (%)

46.15

100

0.001

  1. Vitamin B12 categories were grouped as follows: Clinical deficiency (<140 pmol/L), Metabolic deficiency/metabolic risk (140–400 pmol/L), and Metabolic safety (>400 pmol/L). Folate categories were grouped as follows: Clinical deficiency/risk of insufficiency (<4 ng/mL) and Metabolic safety/elevated (>4 ng/mL).
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