Fig. 1 | European Journal of Human Genetics

Fig. 1

From: Older mothers and increased impact of prenatal screening: stable livebirth prevalence of trisomy 21 in the Netherlands for the period 2000–2013

Fig. 1

Model for estimating livebirth prevalence of T21. Correction rates of natural foetal loss for women screened by amniocentesis was 25% (therefore survival to term 1−0.25 = 0.75) and foetal loss rates for women screened by CVS were approximately 32% (therefore survival to term 1−0.32 = 0.68)* each year by age of mother at the time of birth, from 15 years till 60 years old. AC_ToP termination of pregnancy following positive amniocentesis, CVS_ToP termination of pregnancy following positive chorionic villus sampling

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