Table 1 Results of the candidate gene association analysis

From: Next-generation sequencing identified SPATC1L as a possible candidate gene for both early-onset and age-related hearing loss

Trait

SNP

Chr

Position

Effect allele

Other allele

Eff. all. freq

N

Beta

SE beta

P-value

PTAL

rs14378

21

47581423

T

C

0.054

598

0.05334218

0.02481052

0.031556621

PTAL

rs113710653

21

47581835

T

C

0.039

590

0.07971061

0.02879945

0.005643919

PTAL

rs113146399

21

47581949

T

C

0.044

598

0.06031144

0.02721387

0.026677654

PTAM

rs14378

21

47581423

T

C

0.054

597

0.06057786

0.03000266

0.04347863

PTAM

rs113710653

21

47581835

T

C

0.040

589

0.09218281

0.03477333

0.00802626

PTAM

rs113146399

21

47581949

T

C

0.044

597

0.06870397

0.03287106

0.03660835

PTAH

rs14378

21

47581423

T

C

0.054

604

0.006119463

0.04790555

0.8983546

PTAH

rs113710653

21

47581835

T

C

0.039

596

0.02570644

0.05588673

0.6455349

PTAH

rs113146399

21

47581949

T

C

0.044

604

−0.004327187

0.05277132

0.9346476

  1. PTAL pure tone average of low frequencies, PTAM pure tone average of medium frequencies, PTAH pure tone average of high frequencies, Eff. all. freq effect allele frequency, Beta effect size estimate, SE Beta effect size standard error
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