Table 3 Descriptive characteristics of the 1065 Danish persons with NF1 and the 8791 NF1-free persons, born 1965–2000, graduated from grade 9 in Denmark 1981–2015

From: Correction: Educational delay and attainment in persons with neurofibromatosis 1 in Denmark

 

NF1 cohort

NF1-free cohort

 

N

%

Grad.

Person-years

N

%

Grad.

Person-years

Total

1,065

 

932

2,734

8,791

 

7,962

19,274

Gender

 Male

529

50

454

1,416

4,426

50

3,897

10,216

 Female

536

50

478

1,318

4,365

50

4,065

9,058

Pearson χ2(1) = 0.17 Pr. = 0.68

       

Birth year

 1965–1969

107

10

102

260

960

11

916

2,187

 1970–1974

151

14

144

341

1,248

14

1,208

2,687

 1975–1979

136

13

128

351

1,025

12

996

2,278

 1980–1984

133

13

119

412

907

10

869

2,082

 1985–1989

128

12

115

384

934

10

890

2,249

 1990–1994

164

15

153

465

1,375

16

1,314

3,330

 1995–2002

246

23

171

520

2,342

27

1,769

4,461

Pearson χ2 (6) = 12.20 Pr = 0.058

Mother’s education

 Short

343

32

298

891

2,234

25

2,003

5,381

 Medium

502

47

439

1,317

4,273

49

3,914

9,199

 Long

189

18

168

434

2,097

24

1,896

4,211

 Missing

31

3

  

187

2

  

Pearson χ2 (3) = 35.11 Pr = 0.000

Cancera

 Yes

57

5

50

148

49

1

48

102

Pearson χ2 (1) = 205.26 Pr = 0.000

Diseases of bone, joints and soft tissueb

 

76

7

70

192

137

2

126

306

Pearson χ2 (1) = 139.77 Pr = 0.000

Diseases of nervous systemc

 

155

15

126

479

468

5

406

1,136

Pearson χ2 (1) = 136.68 Pr = 0.000

Diseases of circulatory systemd

 

25

2

19

62

34

0

32

72

Pearson χ2 (1) = 61.37 Pr = 0.000

Other medical diseasese

 

533

50

461

1,442

3,071

35

2,746

6,938

Pearson χ2 (1) = 93.54 Pr = 0.000

Anxietyf

 

7

1

5

17

48

1

42

123

Pearson χ2 (1) = 0.21 Pr = 0.645

Autismg

 

23

2

15

92

92

1

75

295

Pearson χ2 (1) = 10.21 Pr = 0.001

ADHDh

 

50

5

39

114

114

1

94

324

Pearson χ2 (1) = 67.03 Pr = 0.000

Autism/ADHD

 

69

7

50

198

199

2

163

601

Pearson χ2 (1) = 63.81 Pr = 0.000

Depression and other psychiatric diseasesi

 

172

16

128

499

497

6

405

1,432

Pearson χ2 (1) = 165.42 Pr = 0.000

Age at graduation (years)

 14–15

  

10

1,047

  

46

8,622

 15–15.5

  

44

501

  

579

4,090

 15.5–16

  

278

413

  

3,189

3,074

 16–16.5

  

348

235

  

3,250

1,260

 16.5–17

  

170

110

  

703

345

 17–18

  

77

83

  

186

315

 18–20

  

5

346

  

9

1,568

  1. aCancer; malignant (ICD-10): C00-C43, C46-C96, B21.0, D30.1-D30.9, D32-D33, D35.2-D35.4, D41.4, D42-D43, D44.3-D44.5, benign (ICD-8): 210–221, 223.0, 224, 225.5–225.6, 226.0–226.1, 226.4–228
  2. bDiseases of bone, joints soft tissue (ICD-8): 720–738, 274, 710–718
  3. cDiseases of nervous system (ICD-8): 290, 320–324, 340–342, 344–347, 349–358, 360–389
  4. dDiseases of circulatory system (ICD-8): 390–398, 400–404, 410–414, 420–438, 440–448, 450–458
  5. eOther medical diseases (ICD-8): 000–136, 240–242, 244–269, 275.4–276, 278–279, 606, 626–628, 280–281, 283–289, 460–519, 520–543, 550–577, 580–605, 607–625, 629, 700–709, 680–686, 690–698, 274, 710–718, 720–738
  6. fAnxiety (ICD-10): F41, Depression (ICD-10): F32
  7. gAutism (ICD-10): F84
  8. hADHD (ICD-10): F90
  9. iDepression and other psychiatric disease (ICD-10): F01–99, excluding F41, F84, F90
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