Table 2 SNVs Diagnoses Rate and Inheritance Patterns in Sporadic Patients with Genetic Hearing Loss
Gene | Total diagnoses | Autosomal dominant | Autosomal recessive | Mitochondrial | X-Linked | |
|---|---|---|---|---|---|---|
Diagnoses | % | Diagnoses | Diagnoses | Diagnoses | Diagnoses | |
GJB2 | 100 | 23.09% | 100 | |||
SLC26A4 | 84 | 19.39% | 84 | |||
12SrRNA | 5 | 1.15% | 5 | |||
MYO15A | 4 | 0.92% | 4 | |||
POU3F4 | 3 | 0.69% | 3 | |||
USH2A | 3 | 0.69% | 3 | |||
MYO1F | 3 | 0.69% | 3 | |||
MYO7A | 3 | 0.69% | 3 | |||
TMC1 | 3 | 0.69% | 3 | |||
TRIOBP | 2 | 0.69% | 2 | |||
CDH23 | 2 | 0.46% | 2 | |||
KCNQ4 | 2 | 0.46% | 2 | |||
ADGRV1 | 1 | 0.23% | 1 | |||
PAX3 | 1 | 0.23% | 1 | |||
MITF | 1 | 0.23% | 1 | |||
CLDN14 | 1 | 0.23% | 1 | |||
OTOA | 1 | 0.23% | 1 | |||
OTOF | 1 | 0.23% | 1 | |||
PDZD7 | 1 | 0.23% | 1 | |||
TECTA | 1 | 0.23% | 1 | |||
TRPN | 1 | 0.23% | 1 | |||
TMPRSS3 | 1 | 0.23% | 1 | |||
KCNQ1 | 1 | 0.23% | 1 | |||
MYO6 | 1 | 0.23% | 1 | |||
Total | 226 | 52.19% | 5 | 213 | 5 | 3 |
