Fig. 2 | European Journal of Human Genetics

Fig. 2

From: Longitudinal changes in the frequency of mosaic chromosome Y loss in peripheral blood cells of aging men varies profoundly between individuals

Fig. 2

Illustration of the non-linear estimation of LOY mosaicism by mLRRY calculated from SNP-array data by comparisons with LOY estimates generated from the same set of samples using independent technologies. a, b show the comparisons between mLRRY calculated from SNP-array data with the corresponding LOY estimates generated from the pairwise studied samples using whole genome sequencing (WGS) and droplet digital PCR (ddPCR), respectively. c displays a high concordance between estimates of LOY in samples pairwise studied with WGS and ddPCR. A linear regression line with Pearson’s coefficient of determination (R2) is shown for each comparison

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