Table 1 Residual heritability for five neuropsychiatric disorders.

From: An epigenetic, transgenerational model of increased mental health disorders in children, adolescents and young adults

Disorder

ASD

ADHD

Bipolar disorder

Depression

Schizophrenia

\(H^2\)

0.924

0.763

0.676

0.579

0.562

\(G_A\) measured

(\(G_{SNP}\) + CNVs)

0.37

(0.17 + 0.2)

40%

0.30

(0.28 + 0.02)

39.3%

0.25

37%

0.21

36%

0.27

(0.23 + 0.04)

48%

Residual H2

0.554

60%

0.463

60.7%

0.426

63%

0.369

63.7%

0.292

52%

Estimated

G effect

[\(G_A(0.5\,E_P) + 0.5\,E_P\)]

0.924

0.568

(0.468 + 0.1)

74.4%

0.468

(0.333 + 0.135)

69.2%

0.373

(0.192 +0.181)

64.2%

0.435

(0.308 +0.127)

77.4%

Residual \(H^2\)

0

0.195

25.6%

0.208

30.8%

0.207

35.8%

0.127

22.6%

  1. Heritability \(H^2\) [72], measured \(G_A = G_{SNP} + {\mathrm{CNVs}}\) [10, 14, 73, 74], Residual \(H^2\), Estimated \(G\left( {\sigma _G^2} \right) = \left( {G_A + 0.5E_P} \right)\) effects (this paper) and Residual \(H^2\) for five major psychiatric disorders. All % are for portion of \(H^2\).
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