Table 2 Baseline characteristics of ALS patients and controls.
From: Genetic analysis of ALS cases in the isolated island population of Malta
ALS (n = 24) | Controls (n = 13) | |
|---|---|---|
Sex | ||
Male, % (n) | 66.7 (16) | 46.2 (6) |
Female, % (n) | 33.3 (8) | 53.8 (7) |
Type | ||
Familial, % (n) | 12.5 (3) | – |
Sporadic, % (n) | 87.5 (21) | – |
Age at onset | ||
Mean year ± SD (range) | 59.3 ± 13.2 (27–80) | – |
Age at recruitment | ||
Mean year ± SD (range) | 63.5 ± 11.6 (30–82) | 71.2 ± 10.9 (52–90) |
ALSFRS-R score, mean ± SD (range) | 25.6 ± 11.1 (11.5–44) | 47.9 ± 0.3 (47–48) |
Site of onset | ||
Spinal, % (n) | 70.8 (17) | – |
Bulbar, % (n) | 25 (6) | – |
Both, % (n) | 4.2 (1) | |
Survival, mean years ± SD (range) | 5.5 ± 5.1 (2-20) | – |
Deceased, % (n) | 62.5 (15) | – |
Cognitive status | ||
Normal, % (n) | 95.8 (23) | 100 (13) |
Impaired, % (n) | 4.2 (1) | 0 (0) |
Environmental risk factors | ||
Heavy smoking, % (n) | 33.3 (8) | 23.1 (3) |
Strenuous activity, % (n) | 54.2 (13) | 23.1 (3) |
Excessive alcohol consumption, % (n) | 8.3 (2) | 7.8 (1) |
CK levels at recruitment, IU/La | ||
Mean in males ± SD (range) | 311.2 ± 259.7 (15–863) | – |
Mean in females ± SD (range) | 180.8 ± 117.5 (38–336) | – |
