Fig. 3: Hearing difficulties (HD) polygenic risk score (PRS) from UK Biobank British genome-wide association study used to predict HD in TwinsUK. | European Journal of Human Genetics

Fig. 3: Hearing difficulties (HD) polygenic risk score (PRS) from UK Biobank British genome-wide association study used to predict HD in TwinsUK.

From: Self-reported hearing loss questions provide a good measure for genetic studies: a polygenic risk score analysis from UK Biobank

Fig. 3

Total variance explained by the PRS for multiple p value thresholds for inclusion of SNPs, with the highest bar indicating the optimal p value threshold, explaining the maximum amount of variance in HD in the target sample. See text for further details.

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