Fig. 1: Study design. | European Journal of Human Genetics

Fig. 1: Study design.

From: Identification of novel locus associated with coronary artery aneurysms and validation of loci for susceptibility to Kawasaki disease

Fig. 1

Flow diagram describes cohorts used in the study. Cohort 1: US subjects; Cohort 2: US and Finnish subjects; Cohort 3: UK and Dutch subjects. We first performed a severity analysis comparing KD subjects who developed CAA with those who did not. We next performed a new susceptibility GWAS comparing KD subjects and healthy controls and meta-analyzed this with GWAS data from the previously reported KD GWAS of European descent subjects [11]. Arrows leaving boxes denote subjects deleted from cohorts following more stringent ethnicity quality control or deleted because of missing information on CA status. Subjects who were classified as having dilated CA were excluded from the severity analysis but included for the susceptibility analysis. CA coronary artery, CAA coronary artery aneurysm.

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