Fig. 1: Forest plots of z-scored polygenic risk scores (PRSs) for multiple sclerosis cases and controls in Generation Scotland, ORCADES and VIKING.
From: Contribution of common risk variants to multiple sclerosis in Orkney and Shetland
PRS calculated using three SNP sets are used for comparison: A. the full SNP set (n = 127), B. the SNP set without HLA-DRB1*15:01 tag SNP rs9271069 (n = 126), and C. a risk score for rs9271069 alone.
