Table 4 Associations between subjects in the 95th percentile vs 5th and third quintile and MM risk with the different types of scores.
From: A polygenic risk score for multiple myeloma risk prediction
Type of score | No of cases | No of controls | Distribution | ORa | 95% CIa | pvalue |
|---|---|---|---|---|---|---|
Unweighted 100% call rate | 202 | 44 | 95% vs 5% | 5.77 | 2.37–14.06 | 1.12 × 10−4 |
476 | 142 | 95% vs third quintile | 4.22 | 2.11–8.44 | 4.52 × 10−5 | |
Unweighted scaled | 356 | 141 | 95% vs 5% | 4.12 | 2.42–7.01 | 1.81 × 10−7 |
745 | 407 | 95% vs third quintile | 3.05 | 2.15–4.32 | 3.73 × 10−10 | |
Weighted 100% call rate | 221 | 97 | 95% vs 5% | 6.81 | 3.52–13.16 | 1.20 × 10−8 |
398 | 241 | 95% vs third quintile | 3.05 | 1.98–4.70 | 4.41 × 10−7 | |
Weighted scaled | 316 | 141 | 95% vs 5% | 4.29 | 2.52–7.30 | 7.95 × 10−8 |
646 | 352 | 95% vs third quintile | 2.41 | 1.68–3.45 | 1.64 × 10−6 |
