Table 2 Survey results: What sort of genetic conditions do you think people would like to be informed about when they take part in genetic research?.

From: Preferences for return of germline genome sequencing results for cancer patients and their genetic relatives in a research setting

 

Probands, n (%)

Relatives, n (%)

Known genetic conditions caused by one gene, for which there is no prevention (e.g. diet, exercise) or treatment that can change the risk (e.g. inherited blindness)

 Yes

216 (65)

121 (61)

 No

13 (4)

9 (5)

 Maybe

73 (22)

40 (20)

 Don’t know

30 (9)

29 (15)

Known genetic conditions caused by one gene, for which there is prevention (e.g. screening) or treatment that can change the risk (e.g. breast or bowel cancer)

 Yes

311 (93)

180 (91)

 No

0

0

 Maybe

6 (2)

11 (6)

 Don’t know

15 (5)

8 (4)

Known genetic conditions caused by many genes, which can have a major impact on health, for which there is treatment as well as lifestyle factors (e.g. diet, exercise, stopping smoking) which can modify the risk (e.g. cancer, heart disease)

 Yes

303 (90)

183 (92)

 No

0

1 (0.5)

 Maybe

15 (5)

7 (4)

 Don’t know

14 (4)

8 (4)

Known genetic conditions caused by many genes, which usually have a lower impact on health, for which there is treatment as well as lifestyle factors which can modify the risk (e.g. asthma)

 Yes

285 (85)

174 (87)

 No

2 (0.6)

4 (2)

 Maybe

27 (8)

13 (7)

 Don’t know

18 (5)

8 (4)