Fig. 3: Linkage disequilibrium (LD) between lead SNPs.

Haploview LD plot showing the lead SNPs in the PCSK9 locus associated with cardiometabolic or psychiatric traits, and the SNPs included in PGS4 (*) and PGS7 (#). Each box provides estimated statistics of % frequency of coinheritance (r² values). Darker shaded boxes represent stronger LD (r² colours).