Supplementary Table 3 Genotype to predicted phenotype translation to be programmed into laboratory information system.
Genotype | rs number variants | Nucleotide at position | Predicted phenotype |
|---|---|---|---|
UGT1A1: WILDTYPE/WILDTYPE | UGT1A1_rs35350960 UGT1A1_rs4148323 UGT1A1_rs8175347 | C:C G:G -:- | *1/*1 (TA6/TA6) |
UGT1A1:*28/*37/*28/*37 | UGT1A1_rs35350960 UGT1A1_rs4148323 UGT1A1_rs8175347 | C:C G:G TA:TA | *28/*28 (TA7/TA7) |
UGT1A1:WILDTYPE/*28/*37 | UGT1A1_rs35350960 UGT1A1_rs4148323 UGT1A1_rs8175347 | C:C G:G -:TA | *1/*28 (TA6/TA7) |
UGT1A1:*27/*27 | UGT1A1_rs35350960 UGT1A1_rs4148323 UGT1A1_rs8175347 | A:A G:G -:- | PM otherwise |
UGT1A1:WILDTYPE/*27 | UGT1A1_rs35350960 UGT1A1_rs4148323 UGT1A1_rs8175347 | C:A G:G -:- | IM otherwise |
UGT1A1:WILDTYPE/*27_WILDTYPE/*28/*37 | UGT1A1_rs35350960 UGT1A1_rs4148323 UGT1A1_rs8175347 | C:A G:G -:TA | PM otherwise |
UGT1A1:*6/*6 | UGT1A1_rs35350960 UGT1A1_rs4148323 UGT1A1_rs8175347 | C:C A:A -:- | PM otherwise |
UGT1A1:WILDTYPE/*6 | UGT1A1_rs35350960 UGT1A1_rs4148323 UGT1A1_rs8175347 | C:C G:A -:- | IM otherwise |
UGT1A1:WILDTYPE/*6_WILDTYPE/*28/*37 | UGT1A1_rs35350960 UGT1A1_rs4148323 UGT1A1_rs8175347 | C:C G:A -:TA | PM otherwise |
UGT1A1:WILDTYPE/*27_WILDTYPE/*6 | UGT1A1_rs35350960 UGT1A1_rs4148323 UGT1A1_rs8175347 | C:A G:A -:- | PM otherwise |
