Fig. 3: Correlation between genotype and age at onset in our cohort. | European Journal of Human Genetics

Fig. 3: Correlation between genotype and age at onset in our cohort.

From: The genetic landscape and clinical implication of pediatric Moyamoya angiopathy in an international cohort

Fig. 3

A Age at MMA symptom onset for RNF213 patients compared to all non-RNF213 as well as to all non-RNF213 with MMD. B Age at MMA symptom onset for patients with a clinical diagnosis of NF1 compared to all other patients in our cohort. Patients diagnosed by MRI in the asymptomatic phase as well as NF1 patients with additional RNF213 (possibly) deleterious variants were excluded from this analysis. Lines and whiskers represent mean ± SD. ns non-significant, *p < 0.05, **p < 0.01 by two-tailed Mann–Whitney test.

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