Fig. 2: Decade-wise audiograms for POU4F3 c.37delC carriers in the North American kindred show variability in progression and severity.

Each POU4F3 c.37delC carrier is represented by a unique colored line to track hearing loss progression. The unique PID (plus number of audiograms) is provided to the right of each graphic margin. The text box (bottom left) in each graphic gives the number (N) of POU4F3 c.37delC carriers and the total number of audiograms that were available per decade. Only a subset of POU4F3 c.37delC carriers have audiograms for each decade.