Fig. 1: Genome-wide association studies of six lipid traits. | European Journal of Human Genetics

Fig. 1: Genome-wide association studies of six lipid traits.

From: GWAS of lipids in Greenlanders finds association signals shared with Europeans and reveals an independent PCSK9 association signal

Fig. 1: Genome-wide association studies of six lipid traits.The alternative text for this image may have been generated using AI.

A Manhattan plot for each trait. Association signals have been truncated at −log(p) = 15 indicated by pink dots. The dashed line indicates genome-wide significance (p < 5 × 10−8). B Effect size estimates (beta) and significance level (p) for all combinations of the six lipid traits and the lead variants from the 11 genome-wide significant loci identified in the GWAS. ApoA1 apolipoprotein A1, apoB apolipoprotein B. HDL-C HDL-cholesterol, LDL-C, LDL-cholesterol, TC total cholesterol, TG, triglycerides.

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