Fig. 4: Somatic instability of the CAG repeats of a 33 CAG allele carrier. | European Journal of Human Genetics

Fig. 4: Somatic instability of the CAG repeats of a 33 CAG allele carrier.

From: Somatic CAG repeat instability in intermediate alleles of the HTT gene and its potential association with a clinical phenotype

Fig. 4

Somatic expansion ratio in single 33 CAG molecule data, showing the proportion of expansions generated by PCR (only +1 CAG) (blue), and in peripheral blood (orange) and brain tissues (a). The proportion of reads relative to the inherited CAG length in the cerebellum (b) and putamen (c). Caud N caudate nucleus, Occip L occipital lobe, Temp L temporal lobe, Front L frontal lobe, Subst N substantia nigra, HPC hippocampus.

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