Table 1 MMR testing according to patient and tumour characteristics.

From: Identification of people with Lynch syndrome from those presenting with colorectal cancer in England: baseline analysis of the diagnostic pathway

 

MMR tested?

 

No (n | %)

Yes (n | %)

χ2 p value

Total

21,199

56.3%

16,463

43.7%

 

Age

    

<0.001

  10–29

40

38.1%

65

61.9%

 

  30–39

228

31.1%

504

68.9%

 

  40–49

450

30.9%

1006

69.1%

 

  50–54

675

40.4%

995

59.6%

 

  55–59

1289

47.2%

1444

52.8%

 

  60–64

1965

49.7%

1986

50.3%

 

  65–69

2239

50.4%

2203

49.6%

 

  70–74

3472

54.2%

2935

45.8%

 

  75–79

3196

57.4%

2374

42.6%

 

  80–84

3501

64.8%

1904

35.2%

 

  85–89

2670

76.0%

842

24.0%

 

  90+

1474

87.8%

205

12.2%

 

Gender

    

0.001

  Female

9581

57.2%

7161

42.8%

 

  Male

11,618

55.5%

9302

44.5%

 

Ethnicity

    

<0.001

  Asian

363

43.8%

466

56.2%

 

  Black

261

43.5%

339

56.5%

 

  Chinese

46

48.9%

48

51.1%

 

  Mixed

79

52.3%

72

47.7%

 

  Other

250

52.1%

230

47.9%

 

  Unknown

1689

60.2%

1117

39.8%

 

  White

18,511

56.6%

14,191

43.4%

 

Socioeconomic deprivation quintile

    

<0.001

  1—Most deprived

3571

59.2%

2463

40.8%

 

  2

3753

55.6%

3000

44.4%

 

  3

4584

57.3%

3410

42.7%

 

  4

4720

55.9%

3720

44.1%

 

  5—Least deprived

4571

54.2%

3870

45.8%

 

Cancer alliance

    

<0.001

  Cheshire and Merseyside

1497

82.6%

315

17.4%

 

  East Midlands

1691

49.5%

1724

50.5%

 

  East of England—North

1399

63.8%

793

36.2%

 

  East of England—South

1255

54.1%

1065

45.9%

 

  Greater Manchester

1424

80.8%

338

19.2%

 

  Humber, Coast and Vale

332

31.2%

731

68.8%

 

  Kent and Medway

874

70.2%

371

29.8%

 

  Lancashire and South Cumbria

883

67.0%

435

33.0%

 

  North Central and East London

580

41.2%

829

58.8%

 

  North East and Cumbria

1561

66.7%

780

33.3%

 

  North West and South West London

1015

59.0%

706

41.0%

 

  Peninsula

877

60.4%

576

39.6%

 

  Somerset, Wiltshire, Avon and Gloucestershire

1353

63.1%

792

36.9%

 

  South East London

304

34.9%

566

65.1%

 

  South Yorkshire and Bassetlaw

324

31.7%

698

68.3%

 

  Surrey and Sussex

1423

61.2%

904

38.8%

 

  Thames Valley

688

44.2%

870

55.8%

 

  Wessex

877

46.3%

1016

53.7%

 

  West Midlands

2366

56.8%

1798

43.2%

 

  West Yorkshire and Harrogate

476

29.2%

1156

70.8%

 

Tumour stage

    

<0.001

  I

3614

60.0%

2413

40.0%

 

  II

3740

47.9%

4076

52.1%

 

  III

4555

47.4%

5045

52.6%

 

  IV

4314

59.0%

3000

41.0%

 

  Unknown

4976

72.1%

1929

27.9%

 

Tumour grade

    

<0.001

  1

868

67.2%

424

32.8%

 

  2

10,842

47.2%

12,117

52.8%

 

  3

2200

46.3%

2550

53.7%

 

  4

29

72.5%

11

27.5%

 

  Unknown

7260

84.2%

1361

15.8%

 
  1. Data shown as absolute numbers and proportions.