Fig. 2: Power to detect risk alleles by carrier frequency and effect size (odds ratio) at a type 1 error probability of 5 × 10−4. | European Journal of Human Genetics

Fig. 2: Power to detect risk alleles by carrier frequency and effect size (odds ratio) at a type 1 error probability of 5 × 10−4.

From: Exome sequencing identifies HELB as a novel susceptibility gene for non-mucinous, non-high-grade-serous epithelial ovarian cancer

Fig. 2: Power to detect risk alleles by carrier frequency and effect size (odds ratio) at a type 1 error probability of 5 × 10−4.The alternative text for this image may have been generated using AI.

A 2630 cases and 15,000 controls—the carrier frequency and effect size corresponding to BRCA1, BRIP1 and RAD51C are shown for reference. B 20,000 cases and 20,000 controls.

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