Fig. 2: Expression of FBXO2, PALM3, TWF1, and TXNDC17 in the human inner ear organoids.
From: Mendelian non-syndromic and syndromic hearing loss genes contribute to presbycusis
The dataset consists of human pluripotent stem cells developed and differentiated into complex inner ear tissue for which single-cell and single-nucleus RNA sequence data have been generated. The X-axis displays the uniform manifold approximation and projection (UMAP) 1 which is used for dimension reduction and on the Y-axis UMAP 2. The scale bar shown for each gene displays normalized gene expression levels which range from low (yellow) to high (red) that have been adjusted for sequence depth. The far-right panel displays the locations of specific inner ear cell types.
