Table 1 Comparisons of four-digit HLA typing genotypes in the UK Biobank African populations.

From: Uncovering genetic diversity and admixture of British Africans with HLA alleles inferred from whole genome sequencing

HLA locus

IMP:02 vs MIS

IMP:02 vs HLA*LA

MIS vs HLA*LA

Proportion of two match

Proportion of one match

Proportion of no match

Proportion of two match

Proportion of one match

Proportion of no match

Proportion of two match

Proportion of one match

Proportion of no match

HLA-A

88.87%

10.46%

0.67%

87.78%

11.88%

0.33%

94.14%

5.52%

0.33%

HLA-B

58.16%

36.32%

5.52%

58.83%

36.15%

5.02%

89.21%

10.54%

0.25%

HLA-C

77.74%

20.17%

2.09%

76.74%

20.84%

2.43%

91.38%

8.12%

0.50%

HLA-DPA1

63.18%

31.63%

5.19%

62.93%

28.03%

9.04%

83.68%

10.38%

5.94%

HLA-DPB1

67.28%

27.78%

4.94%

67.62%

27.87%

4.52%

92.47%

7.36%

0.17%

HLA-DQA1

81.26%

17.49%

1.26%

82.01%

16.74%

1.26%

98.83%

1.17%

0.00%

HLA-DQB1

67.70%

28.95%

3.35%

67.87%

28.87%

3.26%

96.74%

3.18%

0.08%

HLA-DRB1

70.96%

26.03%

3.01%

72.38%

24.52%

3.10%

91.21%

8.45%

0.33%

Overall

71.89%

24.85%

3.25%

72.02%

24.36%

3.62%

92.21%

6.84%

0.95%

  1. IMP:02 HLA alleles imputed by HLA*IMP:02 software, data as provided by UK Biobank itself, MIS Michigan Imputation Server, HLA*LA HLA*LA (linear alignment).