Table 2 Comparisons of HLA allele or haplotype frequencies between UKB overall African population (All) and its homogeneous subgroup (Homo).
Locus/Haplotype | Group | >0.1 | >0.05 | >0.01 | >0.005 | >0.001 | Allele Counts |
|---|---|---|---|---|---|---|---|
HLA-A | All | 1 | 9 | 18 | 24 | 37 | 53 |
Homo | 1 | 9 | 17 | 21 | 34 | 49 | |
HLA-B | All | 1 | 5 | 21 | 30 | 44 | 76 |
Homo | 1 | 8 | 21 | 29 | 36 | 65 | |
HLA-C | All | 2 | 7 | 17 | 18 | 28 | 37 |
Homo | 3 | 6 | 16 | 18 | 21 | 35 | |
HLA-DQA1 | All | 5 | 6 | 7 | 7 | 7 | 8 |
Homo | 4 | 6 | 7 | 7 | 7 | 7 | |
HLA-DQB1 | All | 4 | 5 | 11 | 12 | 15 | 21 |
Homo | 4 | 5 | 11 | 12 | 15 | 19 | |
HLA-DRB1 | All | 1 | 9 | 19 | 22 | 26 | 42 |
Homo | 1 | 9 | 18 | 21 | 23 | 34 | |
HLA-DPA1 | All | 3 | 4 | 6 | 7 | 11 | 13 |
Homo | 4 | 4 | 6 | 7 | 10 | 13 | |
HLA-DPB1 | All | 3 | 5 | 11 | 15 | 22 | 42 |
Homo | 3 | 5 | 11 | 13 | 22 | 35 | |
Locus Overall | All | 20 | 50 | 110 | 135 | 190 | 292 |
Homo | 21 | 52 | 107 | 128 | 168 | 257 | |
HLA-B ~ HLA-C | All | 1 | 4 | 23 | 40 | 96 | 217 |
Homo | 1 | 3 | 24 | 37 | 81 | 183 | |
HLA-DPA1 ~ HLA-DPB1 | All | 3 | 5 | 12 | 19 | 44 | 87 |
Homo | 3 | 5 | 13 | 19 | 40 | 75 | |
HLA-DRB1 ~ HLA-DQA1 ~ HLA-DQB1 | All | 1 | 5 | 27 | 33 | 59 | 111 |
Homo | 1 | 5 | 23 | 31 | 56 | 92 |