Fig. 2: Composition of D4Z4-like sequences and FRG2 family members across the human genome.

Chromosome ideograms showing D4Z4-like loci (1, 3, 4, 9, 10, 13, 14, 15, 18, 21, 22, Y). Red rectangles mark the enlarged regions. Stretches of colored boxes represent the composition of D4Z4-like sequences (see legend). Flanking β-satellite sequences (bsat) are shown. DUX4FL (chr4) is indicated. DUX4L9/DUXc (chr4) and DUX4L26/DUXo (chr3) are shown in teal. FRG2 loci (chr3, 4, 10, 18, 21, 22) are shown in pink. rDNA arrays on acrocentric short arms are shown in blue.