Abstract
Uveitis is a sight-threatening disease. Up to 35% of patients may have impaired vision. Inflammation of the uvea tissue has more than 60 etiologies. Previous reports have shown that 20–40% of uveitis cases were noninfectious. Some of them may be associated with systemic rheumatological and autoimmune diseases but some may affect the eyes only. The epidemiology and clinical situations of some specific uveitis entities vary worldwide because they are influenced by genetic, ethnic, environmental, and socioeconomic factors. The Asia–Pacific region comprises more than 30 countries. Epidemiology and patterns of uveitis vary greatly in this region. However, some uveitis entities, such as Behcet’s disease, sarcoidosis, and Vogt–Koyanagi–Harada disease, are more common in this region. Many studies on the epidemiology, risk factors, and immune pathogenesis of this disease have been conducted. In this article, we review the epidemiology of noninfectious uveitis and special situations of these three uveitis entities in the Asia–Pacific region.
摘要
葡萄膜炎是一种影响视力的疾病。高达35%的患者可能有视力障碍。葡萄膜炎有60多种病因。过去的报告显示20%-40%的葡萄膜炎是非传染性的。其中一部分可能与系统性风湿病和自身免疫病有关, 但一部分只影响眼部。因为受到遗传、种族、环境和社会经济因素的影响, 一些葡萄膜炎的流行病学和临床发病情况在世界各地不同。亚太地区有30多个国家。该地区葡萄膜炎的流行病学和类型差异很大。然而, 一部分葡萄膜炎, 如贝塞氏病、结节病和小柳原田病, 在该地区更为常见。许多作者对该病的流行病学、危险因素和免疫发病机制进行了大量研究。本文综述了非传染性葡萄膜炎的流行病学和亚太地区这三种葡萄膜炎的发病特点。
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This work was supported by Taipei Veterans General Hospital (106 ~ 107;V107B-019) This manuscript was edited by Wallace Academic Editing
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Hsu, YR., Huang, J.CC., Tao, Y. et al. Noninfectious uveitis in the Asia–Pacific region. Eye 33, 66–77 (2019). https://doi.org/10.1038/s41433-018-0223-z
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