Abstract
Purpose
To evaluate the efficacy and safety of Ahmed valve implantation in childhood glaucoma associated with Sturge–Weber syndrome (SWS).
Methods
A retrospective chart review of patients who underwent primary Ahmed valve implantation in childhood glaucoma associated with SWS. The outcome measures were success rate (Intraocular pressure (IOP) >5 and <21 mm Hg without additional surgical maneuver), and operative complications.
Results
Twenty-four eyes of 18 patients were analyzed. Mean IOP (26.21 ± 3.52 to 12.27 ± 1.27 mm Hg) and mean number of anti-glaucoma medicines (3.92 ± 0.28 to 1.5 ± 1) reduced significantly after the surgery at the mean follow-up of 2.12 ± 0.87 years (P = < 0.05). The cumulative probability of success rate was 75% (Confidence Interval 95%, 60 to 100%) by Kaplan–Meier survival curve analysis. Failed eyes [6 (25%)], hyphema [4 (16.67%)], hypotony [3 (12.5%)], choroidal detachment [3 (12.5%)], tube–cornea touch [2 (8.33%), and visually significant cataract [4 (16.67%)] were the complications observed in post-operative period.
Conclusion
Primary Ahmed valve implantation may provide a safe and effective option in the management of childhood glaucoma associated with SWS.
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References
Sullivan TJ, Clarke MP, Morin JD. The ocular manifestations of the Sturge-Weber syndrome. J Pediatr Ophthalmol Strabis. 1992;29:349–56.
Weiss DI. Dual origin of glaucoma in encephalotrigeminal hemangiomatosis. Trans Ophthalmol Soc. 1973;93:477–93.
Cibis GW, Tripathi RC, Tripathi BJ. Glaucoma in Sturge-Weber syndrome. Ophthalmology. 1984;91:1067–71.
Olsen KE, Huang AS, Wright MM. The efficacy of goniotomy/trabeculotomy in early-onset glaucoma associated with the Sturge-Weber syndrome. J AAPOS. 1998;2:365–8.
Ali MA, Fahmy IA, Spaeth GL. Trabeculectomy for glaucoma associated with Sturge-Weber syndrome. Ophthalmic Surg. 1990;21:352–5.
Iwach AG, Hoskins HD Jr, Hetherington J Jr, Shaffer RN. Analysis of surgical and medical management of glaucoma in Sturge-Weber syndrome. Ophthalmology. 1990;97:904–9.
Mandal AK. Primary combined trabeculotomy-trabeculectomy for early onset glaucoma in Sturge-Weber syndrome. Ophthalmology. 1999;106:1621–7.
Gedde SJ, Schiffman JC, Feuer WJ, Herndon LW, Brandt JD, Budenz DL. Treatment outcomes in the Tube Versus Trabeculectomy (TVT) study after five years of follow-up. Am J Ophthalmol. 2012;153:789–803.
Wu SC, Lin KK. Ahmed glaucoma valve implant for childhood glaucoma in Sturge-Weber syndrome with choroidal hemangioma. Chang Gung Med J. 2006;29:528–31.
Hamush NG, Coleman AL, Wilson MR. Ahmed glaucoma valve implant for management of glaucoma in Sturge-Weber syndrome. Am J Ophthalmol. 1999;128:758–60.
Parsa CF. Focal venous hypertension as a pathophysiologic mechanism for tissue hypertrophy, port wine stains, the Sturge Weber syndrome, and related disorders: proof of concept with novel hypothesis for underlying etiological cause. Trans Am Ophthalmol Soc. 2013;111:180–215.
Beck AD, Freedman S, Kammer J, Jin J. Aqueous shunt devices compared with trabeculectomy with Mitomycin-C for children in the first two years of life. Am J Ophthalmol. 2003;136:994–1000.
Pakravan M, Nikkhah H, Yazdani S, Baradaran Rafiei AR. Trabeculectomy with mitomycin C versus Ahmed glaucoma implant with mitomycin C for treatment of pediatric aphakic glaucoma. J Glaucoma. 2007;16:631–6.
Netland PA, Walton DS. Glaucoma drainage implants in pediatric patients. Ophthamic Surg. 1993;24:723–9.
Nassiri N, Nour-Mahdavi K, Colemann AL. Ahmed glaucoma valve in children: a review. Saudi J Ophthalmol. 2011;25:317–27.
Chen TC, Bhatia LS, Walton DS. Ahmed valve surgery for refractory pediatric glaucoma: a report of 52 eyes. J Pediatr Ophthalmol. 2005;42:274–83.
Englert JA, Freedman SF, Cox TA. The ahmed valve in refractory glaucoma. Am J Ophthalmol. 1999;127:34–42.
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Kaushik, J., Parihar, J.K.S., Jain, V.K. et al. Ahmed valve implantation in childhood glaucoma associated with Sturge–Weber syndrome: our experience. Eye 33, 464–468 (2019). https://doi.org/10.1038/s41433-018-0233-x
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DOI: https://doi.org/10.1038/s41433-018-0233-x
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