Abstract
Objectives
To investigate the clinical characteristics of acute retinal necrosis (ARN) with ultra-wide-field imaging (UWFI) and analyse their visual significance.
Methods
Clinical and UWFI records of patients diagnosed with ARN at a single centre over 2 years were reviewed.
Results
In 38 eyes of 35 patients, the clinical manifestations of ARN on UWFI included patchy (12 eyes) or fan-shaped necrotic lesions (26 eyes), retinal arterial obliteration (38 eyes), vitritis (38 eyes), retinal venous haemorrhage (19 eyes), and vitreous haemorrhage (6 eyes). Retinal detachment was associated with the number of retinal quadrants involved (β = 2.145, P = 0.005). LogMAR BCVA at last follow-up was associated with logMAR BCVA at presentation (β = 0.473, P = 0.004) and retinal detachment (β = 0.367, P = 0.020).
Conclusion
UWFI is useful for detecting retinal lesions in ARN, especially peripheral lesions or through opaque media, and provides valuable information concerning visual prognosis.
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Acknowledgements
The authors thank Zhijian Jiang, Jianhong Dong (Department of Ophthalmology, Shanghai Xuhui Central Hospital, Shanghai, China) for their contributions to data collection; and Ruiping Gu (Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China) for revising the paper.
Funding
This work was supported by the National Natural Science Foundation of China under Grant 81570854 and 81770944; the Science and Technology Commission of Shanghai Municipality under Grant 16411953700 and 18411965100; the Shanghai Hospital Development Center under Grant SHDC12016116.
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Lei, B., Zhou, M., Wang, Z. et al. Ultra-wide-field fundus imaging of acute retinal necrosis: clinical characteristics and visual significance. Eye 34, 864–872 (2020). https://doi.org/10.1038/s41433-019-0587-8
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DOI: https://doi.org/10.1038/s41433-019-0587-8
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