Abstract
Optical coherence tomography (OCT) is a non-invasive medical imaging technology that is playing an increasing role in the routine assessment and management of patients with neuro-ophthalmic conditions. Its ability to characterise the optic nerve head, peripapillary retinal nerve fibre layer and cellular layers of the macula including the ganglion cell layer enables qualitative and quantitative assessment of optic nerve disease. In this review, we discuss technical features of OCT and OCT-based imaging techniques in the neuro-ophthalmic context, potential pitfalls to be aware of, and specific applications in more common neuro-ophthalmic conditions including demyelinating, inflammatory, ischaemic and compressive optic neuropathies, optic disc drusen and raised intracranial pressure. We also review emerging applications of OCT angiography within neuro-ophthalmology.
摘要
相干光断层扫描 (OCT) 是一种非侵入性的医学成像技术, 对于神经眼科疾病患者的常规评估和管理中发挥越来越重的要作用。它可以显示视神经乳头、视乳头周围视网膜的神经纤维层和黄斑细胞层 (包括神经节细胞层) 等, 并可对视神经疾病进行定性和定量评估。在这篇综述中, 我们讨论了OCT和基于OCT的成像技术在神经眼科领域的技术特点、需要注意的潜在缺陷、以及在常见神经眼科疾病中的具体应用, 包括脱髓鞘性、炎症性、缺血性和压迫性视神经病变、视盘玻璃膜疣和颅内压升高等疾病。同时, 我们也回顾了OCT血管造影术在神经眼科方面的新兴应用
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Minakaran, N., de Carvalho, E.R., Petzold, A. et al. Optical coherence tomography (OCT) in neuro-ophthalmology. Eye 35, 17–32 (2021). https://doi.org/10.1038/s41433-020-01288-x
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DOI: https://doi.org/10.1038/s41433-020-01288-x
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