Abstract
Introduction
The Aurolab aqueous drainage implant (AADI) is a low-cost glaucoma drainage device that is modelled on the Baerveldt glaucoma implant. Studies on AADI have reported absolute success rates of 41.8–93.1% at 1 year. Most studies report on tube placement in the anterior chamber. We report on results of tube insertion in the sulcus/pars plana.
Material and methods
A retrospective chart review of all patients who had undergone AADI implantation (with insertion of tube in the sulcus/posterior segment) between June 2015 and November 2018 was done. Patients were asked to stop anti-glaucoma medications on the 40th post-operative day.
Results
The mean age was 57.4 ± 13.8 years (n = 30). The mean IOP prior to surgery was 34.4 ± 6.1 mmHg which reduced to 15.4 ± 8.6 mmHg on the 45th post-operative day (p < 0.001). The absolute success at last review was 10% and the qualified success was 80%. The complication rate was 26.7%. Three patients had hypotony related complications noted at/after the 45th day review (none before 40th day). The incidence of ocular motility disturbances was 26.7% though none of the patients reported diplopia. One patient had sideways rotation of the scleral patch graft resulting in tube exposure. This complication was not seen after we shifted to using 9–0 nylon sutures to anchor the graft. Six patients had loss of best corrected visual acuity and one patient developed endophthalmitis. The endophthalmitis was preceded by conjunctival retraction and sloughing off of the scleral patch graft.
Discussion
AADI implantation results in a substantial drop in IOP. However, many patients continue to require anti-glaucoma medications. Allowing overlap of scleral/corneal patch graft onto the scleral flap may be effective in preventing peritubular leak. It may be advisable to use 9–0 nylon sutures to secure the scleral patch graft anti-glaucoma medications can be temporarily suspended after the 40th post-operative day to minimize hypotony related complications. Melting of the scleral patch graft may be an early sign of endophthalmitis. It would be prudent to specifically look for ocular motility problems in patients undergoing AADI implantation.
Similar content being viewed by others
Log in or create a free account to read this content
Gain free access to this article, as well as selected content from this journal and more on nature.com
or
References
Puthuran GV, Palmberg P, Wijesinghe HK, Krishnadas SR, Robin A. Intermediate-term outcomes of an affordable aqueous drainage implant in adults with refractory glaucoma. Ophthalmol Glaucoma. 2019;2:258–66. https://doi.org/10.1016/j.ogla.2019.03.009.
Puthuran GV, Palmberg PF, Wijesinghe HK, Pallamparthy S, Krishnadas SR, Robin AL. Intermediate-term outcomes of Aurolab aqueous drainage implant in refractory paediatric glaucoma. Br J Ophthalmol. 2019. pii: bjophthalmol-2019-314399. https://doi.org/10.1136/bjophthalmol-2019-314399.
Pathak Ray V, Rao DP. Surgical outcomes of a new low-cost nonvalved glaucoma drainage device in refractory glaucoma: results at 1 year. J Glaucoma. 2018;27:433–9.
Senthil S, Gollakota SR, Ali MH, Turaga K, Badakere S, Krishnamurthy R, et al. Comparison of the new low-cost nonvalved glaucoma drainage device with ahmed glaucoma valve in refractory pediatric glaucoma in Indian eyes. Ophthalmol Glaucoma. 2018;1:167–74.
Maheshwari D, Dabke S, Rajagopal S, Kadar MA, Ramakrishnan R. Clinical outcome of a nonvalved Aurolab aqueous drainage implant in posterior segment versus anterior chamber. Indian J Ophthalmol. 2019;67:1303–8.
Kaushik S, Kataria P, Raj S, Pandav SS, Ram J. Safety and efficacy of a low-cost glaucoma drainage device for refractory childhood glaucoma. Br J Ophthalmol. 2017;101:1623–7.
Rathi SG, Seth NG, Kaur S, Thattaruthody F, Kaushik S, Raj S, et al. A prospective randomized controlled study of Aurolab aqueous drainage implant versus Ahmed glaucoma valve in refractory glaucoma: a pilotstudy. Indian J Ophthalmol. 2018;66:1580–5.
Philip R, Chandran P, Aboobacker N, DhavalikarM, Raman GV. Intermediate-term outcome of Aurolab aqueous drainage implant. Indian J Ophthalmol. 2019;67:233–8.
Babu N, Baliga G, Wijesinghe HK, Puthuran GV. Intermediate-term outcomes of pars plana tube insertion of Aurolab aqueous drainage implant for refractory glaucoma. Br J Ophthalmol. 2019. pii: bjophthalmol-2019-314639. https://doi.org/10.1136/bjophthalmol-2019-314639.
Tello C, Espana EM, Mora R, Dorairaj S, Liebmann JM, Ritch R. Baerveldt glaucoma implant insertion in the posterior chamber sulcus. Br J Ophthalmol. 2007;91:739–42.
Lee EK, Yun YJ, Lee JE, Yim JH, Kim CS. Changes in corneal endothelial cells after Ahmed glaucoma valve implantation: 2-year follow-up. Am J Ophthalmol. 2009;148:361–7.
Iwasaki K, Arimura S, Takihara Y, Takamura Y, Inatani M. Prospective cohort study of corneal endothelial cell loss after Baerveldt glaucoma implantation. PLoS ONE. 2018;13:e0201342.https://doi.org/10.1371/journal.pone.0201342.
Mendrinos E, Dosso A, Sommerhalder J, Shaarawy T. Coupling of HRT II and AS-OCT to evaluate corneal endothelial cell loss and in vivo visualization of the Ahmed glaucoma valve implant. Eye. 2009;23:1836–44.
Seo JW, Lee JY, Nam DH, Lee DY. Comparison of the changes in corneal endothelial cells after pars plana and anterior chamber ahmed valve implant. J Ophthalmol. 2015;2015:486832. https://doi.org/10.1155/2015/486832.
Christakis PG, Kalenak JW, Zurakowski D, Tsai JC, Kammer JA, Harasymowycz PJ, et al. The Ahmed Versus Baerveldt study: one-year treatment outcomes. Ophthalmology. 2011;118:2180–9.
Tsoukanas D, Xanthopoulou P, Charonis AC, Theodossiadis P, Kopsinis G, Filippopoulos T. Heterologous, fresh, human donor sclera as patch graft material in glaucoma drainage device surgery. J Glaucoma. 2016;25:558–64.
Sidoti PA. Inferonasal placement of aqueous shunts. J Glaucoma. 2004;13:520–3.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
The authors declare that they have no conflict of interest.
Additional information
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Rajamani, M., Ramamurthy, C., Ramamurthy, S. et al. Outcome of a low-cost glaucoma drainage device with posterior chamber/pars plana insertion of the tube. Eye 35, 901–912 (2021). https://doi.org/10.1038/s41433-020-0994-x
Received:
Revised:
Accepted:
Published:
Version of record:
Issue date:
DOI: https://doi.org/10.1038/s41433-020-0994-x


