Fig. 1: IL-33 stimulated mast cells regulate tight-junction protein expression in RPE.
From: Unravelling the therapeutic potential of IL-33 for atrophic AMD
A Western blot shows ZO-2, Occludin and beta-actin expression in B6RPE-07 lysates (mouse RPE cell line, courtesy of H Xu, Belfast) either cultured in standard media (control), in conditioned media (CM) from bone-marrow-derived mast cells with or without IL-33 stimulation (12 h), or co-cultured by transwell (TW) with treated or untreated mast cells. B Graphs show relative expression by densitometry analysis (*p < 0.05, **p < 0.01; one-way ANOVA with Tukey’s multiple comparisons test).
