Abstract
Purpose
To compare the progression of posterior vitreous detachment (PVD) between eyes that underwent cataract surgery and eyes that did not undergo surgery in non-highly myopic patients.
Methods
One-hundred twenty-five eyes of 125 patients scheduled for phacoemulsification and 125 eyes of 125 age-matched patients who did not undergo surgery were enrolled. PVD status was evaluated using swept-source optical coherence tomography at 2 days (baseline), and 1, 3, 6, and 12 months postoperatively, and classified into five stages: 0 (no), 1 (paramacular), 2 (perifoveal), 3 (peripapillary), and 4 (complete). The PVD stage and incidence of progression to complete PVD were compared between groups.
Results
The mean PVD stage significantly progressed over the 12 months in the surgery group (P = 0.0004), but did not change significantly in the non-surgery group. The PVD stage did not differ significantly between groups at 2 days, or 1, 3, and 6 months postoperatively, but was significantly more progressed in the surgery group than in the non-surgery group at 12 months (P = 0.0390). After adjusting for age, sex, axial length, and baseline PVD stage, the relative risk for progression to complete PVD was 7.1-fold higher in the surgery group than in the non-surgery group (P < 0.0001, 95% confidence interval 2.9–17.3).
Conclusion
PVD progressed significantly faster in eyes after cataract surgery compared with eyes that did not undergo surgery, and the relative risk of progression to complete PVD was approximately seven-fold higher within 1 year, indicating that the risk for PVD-related diseases is high after cataract surgery.
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Acknowledgements
The authors thank Koji Yonemoto, PhD (Ryukyu University, Naha, Japan) for statistical assistance.
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SH: study conception, study design, data analysis/interpretation of data, and writing and revising of the manuscript. MY: data acquisition and final approval. KH: study conception, study design, data acquisition, data analysis/interpretation of data, and writing and revising of the manuscript, and final approval. KT: study conception, study design, data analysis/interpretation of data, and final approval.
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The Institutional Review Board of Hayashi Eye Hospital approved the study protocol.
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Hayashi, S., Yoshida, M., Hayashi, K. et al. Progression of posterior vitreous detachment after cataract surgery. Eye 36, 1872–1877 (2022). https://doi.org/10.1038/s41433-021-01732-6
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DOI: https://doi.org/10.1038/s41433-021-01732-6
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