Table 2 Anti-VEGF biosimilars in developmenta.

From: An update on long-acting therapies in chronic sight-threatening eye diseases of the posterior segment: AMD, DMO, RVO, uveitis and glaucoma

Company

Compound name

Registered clinical trials

Phase

Aflibercept biosimilars

 Amgen

ABP 938

NCT04270747

III

 Alteogen

ALT-L9

NCT04058535

I

 Coherus Biosciences

CHS-2020

 

 Formycon

FYB203

NCT04522167

III

 Momenta/Mylan

MYL-1701P

NCT03610646, NCT04674800

III (both)

 Samsung Bioepis

SB15

NCT04450329

III

Ranibizumab biosimilars

 Coherus Biosciences/Bioeq

FYB201

NCT02611778

III

 Lupin

LUBT010

NCT04690556

III

 Samsung Bioepis

SB11

NCT03150589

III

 Xbrane

Xlucane

NCT03805100

III

Bevacizumab biosimilars

 Outlook therapeutics

ONS-5010

NCT03834753

III

 Pfizer

Bevacizumab-bvzr/Zirabev

Currently only oncology indications

 Amgen/Allergan

Bevacizumab-awwb/MVASI

Currently only oncology indications

  1. aDuration of efficacy to be determined.